Type
International Project
Start Date
03/06/2021
End Date
02/06/2024
Project Website
https://neurotics-project-nato.com/
Staff
Demetrio Raldúa Pérez
Project Leader
Melissa Faria
Researcher
Juliette Bedrossiantz
Researcher
Carlos Barata Martí
Researcher
Benjamí Piña Capó
Researcher
Project Description
Human brain is a great target for chemical terrorism, so NATO nations should be prepared to respond effectively to terrorist threats involving neurotoxic industrial chemicals (neuroTICs). The main objective of this project is to assess the therapeutic potential of AD4 and thioredoxin-mimetic peptides, blood-brain barrier permeable drugs targeting oxidative stress, apoptosis and inflammation, on acute neurotoxic syndromes induced by three common TICs (organophosphorus compounds, acrylamide, organic mercury). Moreover, specific combinations of drugs derived from the analysis of potential therapeutic targets for each toxidrome will be also tested.
This project is supported by: The NATO Science for Peace and Security programme