Benjamí Piña Capó
Research group: Environmental Toxicology
Service: Environmental Toxicogenomics Service
Dr. Benjamin Piña (h-index=34, 166 publications, 4250 citations) is a Molecular Biologist and Biochemist applying molecular techniques to Environmental issues since 2000. He focuses in the development and use of molecular biomarkers, bioassays, and omic techniques for ecotoxicology. Spanish representative at the Risk Assessment Committee of the European Chemicals Agency (RAC–ECHA, 2011-2013).
New generation of drugs protecting against neurotoxic industrial chemicals
Human brain is a great target for chemical terrorism, so NATO nations should be prepared to respond effectively to terrorist threats involving neurotoxic industrial chemicals (neuroTICs). The main objective of this project is to assess the therapeutic potential of AD4 and thioredoxin-mimetic peptides, blood-brain barrier permeable drugs targeting oxidative stress, apoptosis and inflammation, on acute neurotoxic syndromes induced by three common TICs (organophosphorus compounds, acrylamide, organic mercury). Moreover, specific combinations of drugs derived from the analysis of potential therapeutic targets for each toxidrome will be also tested.
This project is supported by: The NATO Science for Peace and Security programme
Start Date: 03/06/2021 – End Date: 02/06/2024
Project Leader: Demetrio Raldúa Pérez
Researchers: Melissa Faria , Juliette Bedrossiantz , Carlos Barata Martí , Benjamí Piña Capó
Funding: International Project
Nanoparticle Emissions from the Transport Sector: Health and Policy Impacts
Air pollution in European cities is still threatening human health, even though EU emission directives have been sharpened over the last 25 years. Adverse health effects of airborne particles are strongly linked to their size. A major fraction of outdoor ultrafine particles is traffic generated from road, rail, air, and sea transportation. The story that nPETS aims to communicate is the life of the sub 100 nm emissions from its creation to its potential path to human beings and animals. The nPETS consortium aims to improve the knowledge of transport generated exhaust and non-exhaust nanoparticle emissions and their impacts on health and new public policies.
It aims to monitor and sample with state-of-the-art particle instruments the sub 100 nm transport generated emissions from shipping, road, rail, and aviation both in field and controlled laboratory environments. Both aged and fresh aerosols will be considered, including primary and secondary volatile and non-volatile particles. Characterising the emissions will be done from shipping, road, rail, and aviation by linking their sizes, chemical compositions, and morphologies to its specific emission sources such as engines, brakes, clutches, and tyres to increase the understanding of the mechanisms behind adverse risks posed by different types and sources of the identified sub 100 nm particles. The effects of nanoparticles from various transport modes and fuels, as well as specific emission sources, will be compared with a focus on markers of relevance for carcinogenesis and inflammation. Living cells will be exposed to collected and real-world primary and aged aerosols as well as primary and aged aerosols generated in the laboratory.
Furthermore, it also aims to evaluate the possible future impact of new policies in this area on public health and linking the impacts with specific emission sources. This should lead to an understanding and quantification of the risks posed by different types and sources.
Start Date: 01/06/2021 – End Date: 31/05/2024
Researchers: Fulvio Amato , Benjamí Piña Capó , José Portugal Minguela , Barend L. van Drooge , Xavier Querol Carceller , Andrés Alastuey Urós , Teresa Moreno Pérez
Funding: European Project
Decision support-based approach for sustainable water reuse application in agricultural production (DSWAP)
The main goal of DSWAP is to develop modular cost- and energy-efficient wastewater treatment systems. By adopting a circular economy approach, it aims for safe and sustainable valorization of wastewater for irrigation, with minimized ecological and agronomic impacts.
Start Date: 01/07/2019 – End Date: 30/06/2023
Project Leader: Josep Maria Bayona Termens
Researchers: Benjamí Piña Capó , Víctor Matamoros Mercadal , Sylvia Mansilla Barrado
Funding: European Project
Green solutions for treating groundwater pollution to meet drinking water directive standards
The main objective of LIFE SPOT is to develop a new treatment process able to remove nitrates and micropollutants from polluted groundwater to produce drinking water of
good quality that meets the Directive 98/83/EC requirements. This will be applied in rural areas (50 inhabitants or <10m3/d, very small water supplies (VSWS)) of the Mediterranean region, promoting the sustainability and resilience of rural areas, agriculture and tourism sectors. Funding: LIFE programme (LIFE18 ENV / ES / 000199) UE